Albino B6 ES cells and germline transmission

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User offline. Last seen 44 years 51 weeks ago. Offline
Joined: 2009-07-01

Hello List,

We are looking into an albino C57 ES cell line for generating transgenic
mice. For those of you out there that have used albino lines do you
have a preferred host embryo that proved better at generating chimeras
that went germline? For example I was wondering if there was a
significant difference between a BDF1 x C57Bl6 embryo host vs a pure
C57Bl6 host or perhaps an entirely different host that proved successful?


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